A small plane crashed into a road in São Paulo, Brazil, around 7:20 a.m. local time Friday, killing both people on board and injuring several people on the ground, according to the city’s fire department.

Six people sustained minor injuries and were not in serious condition. One of them was a motorcyclist who was passing by. The other five were passengers on a bus that was struck by a part of the plane, according to Capt. Ronaldo Melo, a spokesman for São Paulo’s fire department.

Firefighters arrived on the scene just before 7:30 a.m., finding the plane and the bus on fire, Captain Melo said. “The fire was very aggressive,” he added. The bus passengers had all escaped the vehicle before the fire started, he said.

Videos on social media showed the remnants of the plane in flames, as well as a large, black plume of smoke rising into the air.

It’s unclear what caused the incident, but the plane appeared to have crashed shortly after taking off. It struck the Avenida Marques de São Vicente, a major road in the Barra Funda neighborhood, about four miles from the Campo de Marte Airport, where the plane took off.

The plane was on its way to Porto Alegre, nearly 700 miles south of São Paulo.

About three hours after the crash, the fire department had left the scene, Captain Melo said.